Your EDC May Not Be Built for Payments. Our Payment Manager Is.

Site Payments in EDCs are often a fragmented afterthought—leaving clinical teams to struggle with disconnected, insufficient tools and manual workarounds. Hypha Payment Manager automates payment eligibility checks, generates invoices, and centralizes budgeting—eliminating spreadsheets and inefficiencies for good.

How Much Are EDC Payment Gaps Costing You?

EDCs were never built for clinical trial payments—yet teams are forced to rely on them, leading to hidden financial losses, inefficiencies, and site and team frustrations. Every missing automation means more manual work, miscalculations, and preventable revenue drain.

Lost Hours, Lost Money — Your team spends countless hours manually verifying payments, reconciling invoices, and fixing spreadsheet errors, across multiple platforms; time that could be spent managing studies more effectively.

Inflexible Payment Logic = Overpayments & Disputes — Many EDC payment modules can’t handle complex payment rules, leading to overpayments, disputes,—or worse, unpaid work that creates friction with sites.

Budget Amendments Are a Nightmare — Every contract change means manual recalculations and tracking across disconnected tools. One missed update? That’s an accounting error waiting to happen. Hypha easily updates active budgets based on CTA amendments.

Lack of Visibility = Financial Blind Spots With payments scattered across spreadsheets and EDC workarounds, teams struggle to track spending in real time—leading to budget overruns and compliance risks.

Every financial inefficiency adds up. How much is your EDC really costing you?

Stop Letting Your EDC Cost You Money — There's a Better Way.

We get it—your EDC wasn’t built for budgeting and payments, yet you’re stuck trying to make it work. Manually tracking site payments, reconciling invoices across platforms, and struggling with budget amendments shouldn’t be part of your job.

That’s why we built the Payment Manager—a platform designed to fill the financial gaps your EDC leaves behind. With automated payment logic and built-in invoice management, you gain full control over trial finances—without the manual work.

With our Payment Manager, teams like yours will eliminate costly payment errors, reduce site disputes, and streamline financial reporting.

It’s time to stop fighting your tools and start managing payments with confidence.

What you can expect...

Program Complex Payment Scenarios with Ease

EDCs weren’t built for financial automation. Payment Manager lets you create custom payment rules that adapt to any contract—so you never overpay, underpay, or rely on manual workarounds again.

Implement Budget Amendments Without Breaking Your Workflow

Unlike EDCs, The Payment Manager updates payments automatically when budgets change—so you avoid tracking errors, eliminate recalculations, and stay audit-ready.

Replace Spreadsheets with a Single System

The Payment Manager centralizes payments, invoices, and budgets — so you reduce inefficiencies and wasted time, which means your team can focus on running studies, not fixing financial gaps.

Here's how to start...

Step 1

Request Beta Access

What Happens? – Sign up to join the exclusive beta group and be among the first to experience The Payment Manager.

Step 2

Use The Payment Manager for Free

Once the beta is released, you’ll get one free study to test the Payment Manager with no commitment.

Step 3

Scale & Upgrade

After beta, you can continue using Payment Manager for your existing study. Upgrade to manage additional studies.

What You'll Get

All-in-One Financial Management

Bring budgets, invoices, and payments together — so you can stop juggling spreadsheets.

Automated Payment Logic

Ensure site payments follow contract terms with precision — no more manual calculations or disputes.

Seamless Budget Amendments

Automatically update payments when budgets change — no more EDC updates, tracking errors, or misaligned payments.

Custom Payment Rules

Adapt to any contract or site agreement — ensuring every payment is calculated correctly, every time.

No IT Required

The Payment Manager is built for research professionals, not IT teams — set up in hours, not months.

Holdbacks & Milestones

Control when payments are released based on site progress, ensuring compliance and financial accuracy.

Frequently Asked Questions

Payment Manager is designed for fast, hassle-free onboarding—you can be up and running in hours, not weeks. No complex setup, no IT team required.

No! The Budget Manager is web-based and requires no IT involvement or installations. It’s designed for clinical trial teams, not tech experts.

Yes! We use enterprise-grade security, encryption, and compliance measures to protect your data at all times.

EDCs weren’t built for payments. Payment Manager fills the financial gaps, integrating seamlessly with your existing workflow without replacing your EDC.

Yes! The Payment Manager integrates with EDCs like iMedNet, TrialKit, and others to handle payments without disrupting your current workflow. 

Take Control of Site Payments

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